Sugi Predict

Sugi Predict / Compounds / SCHEMBL29913332

SCHEMBL29913332

SCHEMBL29913332

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)[C@@H](C)O)C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)O)[C@@H](C)O)C(C)C)[C@@H](C)CC

nearest known ligand 0.74

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 16/20 0.74
▸ ECE1 P42892 1/20 0.74
▸ MUS81 Q96NY9 1/20 0.74
▸ CCKBR P32239 1/20 0.67
▸ IL23R Q5VWK5 3/20 0.67
▸ PTH1R Q03431 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30216755 0.96 GLP1R (0.72) GLP1RECE1MUS81CCKBRIL23R
SCHEMBL29742146 0.95 IL23R (0.67) GLP1RECE1MUS81CCKBRIL23R
SCHEMBL29942531 0.94 GLP1R (0.78) GLP1RECE1MUS81CCKBR
SCHEMBL30432072 0.93 GLP1R (0.66) GLP1RECE1MUS81CCKBRIL23R
SCHEMBL29683668 0.93 GLP1R (0.65) GLP1RECE1MUS81CCKBRIL23R
SCHEMBL30567741 0.92 NR3C1 (0.72) GLP1RECE1MUS81CCKBRIL23R
SCHEMBL30299221 0.92 GLP1R (0.73) GLP1RECE1MUS81CCKBRPTH1R
SCHEMBL30005503 0.92 GLP1R (0.77) GLP1RECE1MUS81CCKBR
SCHEMBL29454666 0.92 GLP1R (0.75) GLP1RECE1MUS81CCKBRPTH1R
SCHEMBL31060658 0.92 GLP1R (0.89) GLP1RECE1MUS81CCKBRPTH1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3568409-B1 AGENT FOR PROMOTING ANGIOGENESIS AND USES THEREOF VASOMUNE THERAPEUTICS INC (CA) 2022-12-21 — — EP disclosed
US-20220372095-A1 AN AGENT FOR PROMOTING ANGIOGENESIS AND METHODS AND USES THEREOF VASOMUNE THERAPEUTICS INC (CA) 2022-11-24 — — US disclosed
US-11384130-B2 Agent for promoting angiogenesis and methods and uses thereof VASOMUNE THERAPEUTICS INC. (CA) 2022-07-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220372095-A1 AN AGENT FOR PROMOTING ANGIOGENESIS AND METHODS AND USES THEREOF VEGFA, PGF, FLT4 GLP1R 1072/4885ECE1 184/4885MUS81 4084/4885
US-11384130-B2 Agent for promoting angiogenesis and methods and uses thereof VEGFA, PGF, FLT4 GLP1R 940/4885ECE1 194/4885MUS81 4086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.