Sugi Predict

Sugi Predict / Compounds / SCHEMBL30567788

SCHEMBL30567788

SCHEMBL30567788

CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ EP300 Q09472 1/20 0.58
▸ HIF1A Q16665 1/20 0.58
▸ NPY2R P49146 7/20 0.55
▸ NPY4R P50391 7/20 0.55
▸ NPY5R Q15761 7/20 0.55
▸ NPY1R P25929 5/20 0.55
▸ NTSR1 P30989 6/20 0.54
▸ NTSR2 O95665 5/20 0.54
▸ CALCR P30988 5/20 0.54
▸ SORT1 Q99523 4/20 0.53
▸ RAMP3 O60896 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30648466 0.88 CALCR (0.59) NPY2RNPY4RNPY5RNPY1RNTSR1
SCHEMBL30608553 0.87 NPY2R (0.68) EP300HIF1ANPY2RNPY4RNPY5R
SCHEMBL31256951 0.86 NTSR1 (0.57) NTSR1NTSR2SORT1
SCHEMBL30607406 0.86 NPY2R (0.61) EP300HIF1ANPY2RNPY4RNPY5R
SCHEMBL29758902 0.86 NPY2R (0.54) NPY2RNPY4RNPY5RNPY1RNTSR1
SCHEMBL30432286 0.86 CRHR1 (0.55) EP300HIF1ANPY2RNPY4RNPY5R
SCHEMBL30622604 0.85 NTSR1 (0.59) NTSR1NTSR2SORT1
SCHEMBL31233948 0.85 SLC6A2 (0.61) NTSR1NTSR2SORT1
SCHEMBL31233933 0.85 SLC6A2 (0.61) NTSR1NTSR2SORT1
SCHEMBL30476536 0.85 NTSR2 (0.57) NTSR1NTSR2SORT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240277841-A2 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-08-22 — — US disclosed
US-20240024473-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PURDUE RESEARCH FOUNDATION (US) 2024-01-25 — — US disclosed
CN-116601290-A Human chimeric antigen receptor neutrophils, compositions, kits and methods of use 普渡研究基金会 2023-08-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240277841-A2 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PBK, KIT, MYD88 EP300 2453/4885HIF1A 1072/4885NPY2R 3831/4885
US-20240024473-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PBK, KIT, MYD88 EP300 2453/4885HIF1A 1072/4885NPY2R 3831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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