Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27218802 | 0.86 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1USP2HPGDKMT2A | |
| SCHEMBL31494353 | 0.86 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1USP2HPGDKMT2A | |
| SCHEMBL27218795 | 0.86 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1USP2HPGDKMT2A | |
| SCHEMBL29807971 | 0.82 | NOTUM (0.50) | SMN1; SMN2ALDH1A1USP2HPGDKMT2A | |
| SCHEMBL27218831 | 0.82 | ADORA2A (0.40) | SMN1; SMN2ALDH1A1USP2HPGDKMT2A | |
| SCHEMBL31494398 | 0.82 | ADORA2A (0.40) | SMN1; SMN2ALDH1A1USP2HPGDKMT2A | |
| SCHEMBL29807952 | 0.81 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1USP2HPGDKMT2A | |
| SCHEMBL29807903 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1USP2HPGDKMT2A | |
| SCHEMBL29808327 | 0.80 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1USP2HPGDKMT2A | |
| SCHEMBL31494377 | 0.79 | ADORA2A (0.39) | SMN1; SMN2ALDH1A1USP2HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745289-A | Agonists of free fatty acid receptor 1 and their use in diseases associated with said receptor | 奥洛治疗有限公司 | 2023-09-12 | — | — | CN | disclosed |