Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29807903 | 0.90 | SMN1; SMN2 (0.51) | NOTUMALDH1A1SMN1; SMN2HPGDUSP2 | |
| SCHEMBL29807990 | 0.88 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HPGDUSP2LMNA | |
| SCHEMBL29807952 | 0.86 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2HPGDUSP2LMNA | |
| SCHEMBL26424898 | 0.84 | NOTUM (0.57) | NOTUMALDH1A1SMN1; SMN2HPGDUSP2 | |
| SCHEMBL30567828 | 0.82 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2HPGDUSP2LMNA | |
| SCHEMBL26424635 | 0.82 | NOTUM (0.52) | NOTUMALDH1A1SMN1; SMN2HPGDUSP2 | |
| SCHEMBL26424620 | 0.82 | SMN1; SMN2 (0.49) | NOTUMALDH1A1SMN1; SMN2HPGDUSP2 | |
| SCHEMBL31494335 | 0.82 | SMN1; SMN2 (0.49) | NOTUMALDH1A1SMN1; SMN2HPGDUSP2 | |
| SCHEMBL29808327 | 0.82 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2HPGDUSP2LMNA | |
| SCHEMBL29808165 | 0.81 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2HPGDUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220274968-A1 | Oxazole And Oxadiazole Derivatives Useful As Agonists Of Free Fatty Acid Receptor 1 | GBIOTECH S.À.R.L. (CH) | 2022-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220274968-A1 | Oxazole And Oxadiazole Derivatives Useful As Agonists Of Free Fatty Acid Receptor 1 | FFAR2, FFAR1, FFAR3 | NOTUM 1056/4885ALDH1A1 1197/4885SMN1; SMN2 3576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.