SCHEMBL30568043

SCHEMBL30568043

COc1ccc(C#Cc2ccccc2)c(N)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
MAPT P10636 4/20 0.55
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
CYP3A4 P08684 3/20 0.55
KDM4E B2RXH2 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
NPC1 O15118 2/20 0.55
CYP1A2 P05177 2/20 0.55
CYP2C9 P11712 1/20 0.55
HPGD P15428 1/20 0.55
CYP2C19 P33261 1/20 0.55
HSD17B10 Q99714 1/20 0.55
APP P05067 3/20 0.49
PTPN1 P18031 1/20 0.46
PTPN11 Q06124 1/20 0.46
THRB P10828 2/20 0.44
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20473150 1.00 ALDH1A1 (0.55) ALDH1A1MAPTMEN1KMT2ACYP3A4
SCHEMBL22245707 0.85 APP (0.51) ALDH1A1MAPTMEN1KMT2ACYP3A4
SCHEMBL1120921 0.82 CSF1R (0.47) CYP3A4CYP1A2CYP2C9CYP2C19CYP2A6
SCHEMBL1921687 0.80 ACACB (0.53) MEN1KMT2ANPC1CYP1A2APP
SCHEMBL13931953 0.80 TUBB4A (0.50) ALDH1A1MAPTMEN1KMT2ACYP3A4
SCHEMBL28296194 0.79 ALDH1A1 (0.63) ALDH1A1MAPTMEN1KMT2ACYP3A4
SCHEMBL29985380 0.79 ALDH1A1 (0.58) ALDH1A1MAPTMEN1KMT2ACYP3A4
SCHEMBL19064627 0.77 ALDH1A1 (0.60) ALDH1A1MAPTMEN1KMT2ACYP3A4
SCHEMBL1923029 0.77 ACACB (0.52) ALDH1A1MAPTMEN1KMT2ACYP3A4
SCHEMBL4765815 0.76 ERN1 (0.49) ALDH1A1MAPTMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118388541-A Organometallic compound, light-emitting device, electronic apparatus, and electronic device 三星显示有限公司 2024-07-26 CN disclosed
CN-110300744-B Compounds for optically active devices 爱尔兰眼力健公司 2023-09-15 CN disclosed