Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 6/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.38 |
| ▸ | PRKACA | P17612 | 2/20 | 0.38 |
| ▸ | FLT1 | P17948 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30568656 | 0.90 | LIMK1 (0.40) | KDM4EHTTHPGDGAAALDH1A1 | |
| SCHEMBL30568674 | 0.84 | LIMK1 (0.54) | KDM4EHPGDGAAALDH1A1GLA | |
| SCHEMBL30568658 | 0.78 | LIMK1 (0.33) | HPGDLIMK1CHEK1AURKADAPK3 | |
| SCHEMBL30568671 | 0.73 | ALDH1A1 (0.43) | KDM4EALDH1A1LIMK1IKBKB | |
| SCHEMBL15512118 | 0.72 | KDM4E (0.68) | KDM4EHTTHPGDGAAALDH1A1 | |
| SCHEMBL660147 | 0.71 | KDM4E (0.51) | KDM4EHTTHPGDGAAALDH1A1 | |
| SCHEMBL7797444 | 0.69 | ICAM1 (0.52) | KDM4EHTTHPGDGAAALDH1A1 | |
| SCHEMBL5554265 | 0.68 | KDM4E (0.43) | KDM4EHTTHPGDGAAALDH1A1 | |
| SCHEMBL19769208 | 0.68 | MAPT (0.40) | KDM4EHTTHPGDALDH1A1LIMK1 | |
| SCHEMBL5554164 | 0.68 | KDM4E (0.42) | KDM4EHTTHPGDGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116730995-A | Hydrazide compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-09-12 | — | — | CN | disclosed |