Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 5/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PAK4 | O96013 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | LTK | P29376 | 1/20 | 0.35 |
| ▸ | GRK5 | P34947 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30568581 | 0.90 | KDM4E (0.42) | LIMK1IKBKBKDM4EHTTCHEK1 | |
| SCHEMBL30568674 | 0.84 | LIMK1 (0.54) | LIMK1IKBKBKDM4EHPGDGAA | |
| SCHEMBL30568658 | 0.76 | LIMK1 (0.33) | LIMK1IKBKBCHEK1AURKADAPK3 | |
| SCHEMBL30568671 | 0.76 | ALDH1A1 (0.43) | LIMK1IKBKBKDM4EALDH1A1MAPT | |
| SCHEMBL2176216 | 0.71 | LIMK1 (0.45) | LIMK1IKBKBKDM4EHTTCHEK1 | |
| SCHEMBL19769208 | 0.65 | MAPT (0.40) | LIMK1IKBKBKDM4EHTTCDK8 | |
| SCHEMBL15512118 | 0.64 | KDM4E (0.68) | LIMK1IKBKBKDM4EHTTCHEK1 | |
| SCHEMBL660147 | 0.62 | KDM4E (0.51) | LIMK1IKBKBKDM4EHTTCHEK1 | |
| SCHEMBL7797444 | 0.62 | ICAM1 (0.52) | LIMK1IKBKBKDM4EHTTCHEK1 | |
| SCHEMBL15286333 | 0.61 | KDM4E (0.47) | KDM4EHPGDALDH1A1EEDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116730995-A | Hydrazide compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-09-12 | — | — | CN | disclosed |