Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 15/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20945421 | 1.00 | KCNJ1 (0.65) | KCNJ1KCNH2MAPTGRM5LMNA | |
| SCHEMBL30569153 | 0.93 | KCNJ1 (0.57) | KCNJ1KCNH2MAPTGRM5LMNA | |
| SCHEMBL20945399 | 0.93 | KCNJ1 (0.57) | KCNJ1KCNH2MAPTGRM5LMNA | |
| SCHEMBL16852992 | 0.86 | KCNJ1 (0.73) | KCNJ1KCNH2 | |
| SCHEMBL30569178 | 0.85 | KCNJ1 (0.77) | KCNJ1KCNH2 | |
| SCHEMBL19513100 | 0.85 | KCNJ1 (0.77) | KCNJ1KCNH2 | |
| SCHEMBL30569165 | 0.82 | KCNJ1 (0.58) | KCNJ1KCNH2GRM5 | |
| SCHEMBL19513099 | 0.82 | KCNJ1 (0.58) | KCNJ1KCNH2GRM5 | |
| SCHEMBL16853002 | 0.82 | KCNJ1 (0.72) | KCNJ1KCNH2 | |
| SCHEMBL19512836 | 0.81 | KCNJ1 (0.72) | KCNJ1KCNH2MAPTGRM5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3445762-B1 | SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2023-09-13 | — | — | EP | claimed |
| EP-3445762-B1 | SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2023-09-13 | — | — | EP | disclosed |