Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23904829 | 0.74 | ACHE (0.41) | PDGFRBPDGFRA | |
| SCHEMBL24478653 | 0.73 | FYN (0.46) | PDGFRBPDGFRAJAK2JAK1TYK2 | |
| SCHEMBL24478445 | 0.73 | KIT (0.42) | PDGFRBPDGFRAJAK2JAK1TYK2 | |
| SCHEMBL30569750 | 0.73 | NQO2 (0.49) | PDE10APDE2APDE5APDE11A | |
| SCHEMBL29804794 | 0.72 | PDGFRB (0.52) | PDGFRBPDGFRAJAK2JAK1TYK2 | |
| Hydrochloric Acid SCHEMBL29665260 | 0.72 | FYN (0.45) | PDGFRBPDGFRAJAK2JAK1TYK2 | |
| SCHEMBL29665271 | 0.72 | KIT (0.41) | PDGFRBPDGFRAJAK2JAK1TYK2 | |
| Hydrochloric Acid SCHEMBL28859453 | 0.71 | PDGFRB (0.51) | PDGFRBPDGFRAJAK2JAK1TYK2 | |
| Hydrochloric Acid SCHEMBL29665261 | 0.71 | FYN (0.44) | PDGFRBPDGFRAJAK2JAK1TYK2 | |
| SCHEMBL23717242 | 0.71 | HDAC4 (0.36) | FYNCYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116583510-A | (aza) quinolin-4-amine derivatives as P2X3 inhibitors | 奇斯药制品公司 | 2023-08-11 | — | — | CN | disclosed |