SCHEMBL30570525

SCHEMBL30570525

N=C=O.N=C=O.O=C1NC(=O)c2cccc1c2

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTP4A3 O75365 2/20 0.39
PTP4A2 Q12974 1/20 0.39
PTP4A1 Q93096 1/20 0.39
GSK3B P49841 5/20 0.37
PTGS2 P35354 3/20 0.36
PARP1 P09874 1/20 0.35
BRAF P15056 1/20 0.33
GRM5 P41594 2/20 0.33
MAOA P21397 2/20 0.32
MAOB P27338 2/20 0.32
CASP3 P42574 1/20 0.32
CASP2 P42575 1/20 0.32
CASP7 P55210 1/20 0.32
CASP6 P55212 1/20 0.32
CASP8 Q14790 1/20 0.32
CHEK1 O14757 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6053309 0.88 GSK3B (0.46) PTP4A3PTP4A2PTP4A1GSK3BPTGS2
SCHEMBL11121175 0.80
SCHEMBL5949251 0.76 PTP4A3 (0.39) PTP4A3PTP4A2PTP4A1GSK3BPTGS2
Ethane SCHEMBL27586515 0.75 CYP3A4 (0.41) MAOA
Ethylene SCHEMBL1254021 0.75 MEN1 (0.40) MAOA
SCHEMBL1133537 0.73 PTGS2 (0.57) GSK3BPTGS2
SCHEMBL1246496 0.72 MEN1 (0.36) PTP4A3GSK3BPTGS2MAOAMAOB
Adipic Acid SCHEMBL31357385 0.70 F13A1 (0.43) PTGS2CASP3
Nitrogen SCHEMBL7672060 0.68 JAK2 (0.43) PTP4A3PTP4A2PTP4A1GSK3BPTGS2
Biphenyl SCHEMBL28823247 0.67 GSK3A (0.48) GSK3BMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119285499-A Preparation method of m-xylylene diisocyanate 湖南化工研究院有限公司 2025-01-10 CN claimed
CN-116854422-A Polyurea particle fiber concrete and preparation method thereof 西南科技大学 2023-10-10 CN claimed
CN-119285499-A Preparation method of m-xylylene diisocyanate 湖南化工研究院有限公司 2025-01-10 CN disclosed