SCHEMBL6053309

SCHEMBL6053309

O=C1NC(=O)c2cccc1c2

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 4/20 0.46
PTP4A3 O75365 2/20 0.42
PARP1 P09874 1/20 0.42
PTGS2 P35354 5/20 0.42
PTP4A2 Q12974 1/20 0.40
PTP4A1 Q93096 1/20 0.40
CASP3 P42574 1/20 0.39
CASP2 P42575 1/20 0.39
CASP7 P55210 1/20 0.39
CASP6 P55212 1/20 0.39
CASP8 Q14790 1/20 0.39
MAOA P21397 2/20 0.38
MAOB P27338 2/20 0.38
BRAF P15056 1/20 0.37
ADK P55263 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30570525 0.88 PTP4A3 (0.39) GSK3BPTP4A3PARP1PTGS2PTP4A2
SCHEMBL5949251 0.87 PTP4A3 (0.39) GSK3BPTP4A3PARP1PTGS2PTP4A2
SCHEMBL1133537 0.83 PTGS2 (0.57) GSK3BPTGS2
SCHEMBL1246496 0.82 MEN1 (0.36) GSK3BPTP4A3PTGS2MAOAMAOB
Adipic Acid SCHEMBL31357385 0.79 F13A1 (0.43) PTGS2CASP3NPSR1
Nitrogen SCHEMBL7672060 0.78 JAK2 (0.43) GSK3BPTP4A3PARP1PTGS2PTP4A2
SCHEMBL7132790 0.74 PTGS2 (0.44) GSK3BPTGS2
SCHEMBL9016868 0.74 GSK3B (0.50) GSK3BPTP4A3PARP1PTP4A2PTP4A1
SCHEMBL8767001 0.72 GSK3A (0.58) GSK3BMAOAMAOB
SCHEMBL28274474 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115768752-B Substituted isophthalic acid diamides 拜耳公司 2025-04-22 CN claimed
CN-119463260-A Method for modifying hydrophilic polyelectrolyte multilayer film on surface of hydrophobic polymer particles by using coating machine 刘洪江 2025-02-18 CN claimed
CN-115884967-A Substituted isophthalic acid diamides 拜耳公司 2023-03-31 CN claimed
CN-115768752-A Substituted isophthalic acid diamides 拜耳公司 2023-03-07 CN claimed
CN-115745871-A Synthesis method of N, N' -bis (2, 6-tetramethyl-4-piperidyl) -1, 3-benzenedicarboxamide 江苏极易新材料有限公司 2023-03-07 CN claimed
WO-2022088300-A1 PREPARATION METHOD FOR M-PHENYLENEDIAMINE 山东兴强化工产业技术研究院有限公司 2022-05-05 WO claimed
WO-2022088301-A1 METHOD FOR SYNTHESIZING M-PHENYLENEDIAMINE 山东兴强化工产业技术研究院有限公司 2022-05-05 WO claimed
WO-2022088303-A1 METHOD FOR PREPARING M-PHENYLENEDIAMINE 山东兴强化工产业技术研究院有限公司 2022-05-05 WO claimed
WO-2022088302-A1 PREPARATION METHOD FOR ISOPHTHALAMIDE 山东兴强化工产业技术研究院有限公司 2022-05-05 WO claimed
EP-1272223-B1 THERAPEUTIC AND DIAGNOSTIC LIGAND SYSTEMS COMPRISING TRANSPORT MOLECULE BINDING PROPERTIES AND MEDICAMENTS CONTAINING THE SAME KTB TUMORFORSCHUNGS GMBH (DE) 2006-05-31 EP claimed
US-4780535-A Maleic and phthalic diamides THEODOROPULOS SPYROS (US) 1988-10-25 US claimed
US-20260148876-A1 CONDUCTIVE PARTICLES, CONDUCTIVE MATERIALS USED THE SAME DUK SAN NEOLUX CO., LTD. (KR) 2026-05-28 US disclosed
CN-122091300-A Conductive particle, conductive material, and connection structure 2026-05-26 CN disclosed
EP-4572795-A2 METHODS AND COMPOSITIONS FOR TREATING CANCER WITH CANCER-BINDING ADJUVANTS The University of Chicago (US) 2025-06-25 EP disclosed
CN-119984574-A Pressure sensor and preparation method thereof 深圳大学 2025-05-13 CN disclosed
US-4743691-A INHIBITORS OF ORNITHINE DECARBOXYLASE MERRELL DOW FRANCE ET CIE (FR) 1988-05-10 US disclosed
EP-0046710-B1 PREPARATION OF AMINOACETONITRILE DERIVATIVES MERRELL TORAUDE ET COMPAGNIE (FR) 1984-06-13 EP disclosed
US-4405530-A Process for preparing fluorinated amino-nitriles MERRELL TORAUDE ET COMPAGNIE (FR) 1983-09-20 US disclosed
EP-0046710-A1 Preparation of aminoacetonitrile derivatives MERRELL TORAUDE ET COMPAGNIE (FR) 1982-03-03 EP disclosed
US-4179444-A Process for the manufacture of iso-imides or mixtures of iso-imides and imides CIBA-GEIGY CORPORATION (US) 1979-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260148876-A1 CONDUCTIVE PARTICLES, CONDUCTIVE MATERIALS USED THE SAME NOXO1, SCO2, CAD GSK3B 1381/4885PTP4A3 578/4885PARP1 1771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.