Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 10/20 | 0.65 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.64 |
| ▸ | KDR | P35968 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PROKR1 | Q8TCW9 | 4/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23828266 | 1.00 | CFTR (0.65) | CFTRBAZ2BKDRUSP2CYP1A2 | |
| SCHEMBL29171356 | 0.79 | BAZ2B (0.82) | CFTRBAZ2BKDRUSP2CYP1A2 | |
| SCHEMBL23828254 | 0.78 | CFTR (0.75) | CFTRBAZ2BKDRUSP2CYP1A2 | |
| SCHEMBL31020950 | 0.76 | CFTR (1.00) | CFTRBAZ2BKDRUSP2CYP1A2 | |
| SCHEMBL23828248 | 0.76 | CFTR (1.00) | CFTRBAZ2BKDRUSP2CYP1A2 | |
| SCHEMBL23828253 | 0.76 | CFTR (1.00) | CFTRBAZ2BKDRUSP2CYP1A2 | |
| SCHEMBL23828241 | 0.76 | CFTR (0.75) | CFTRBAZ2BKDRUSP2CYP1A2 | |
| SCHEMBL17447456 | 0.75 | BAZ2B (0.76) | CFTRBAZ2BKDRUSP2CYP1A2 | |
| SCHEMBL12868564 | 0.75 | LMNA (0.78) | CFTRBAZ2BKDRUSP2CYP1A2 | |
| SCHEMBL7042654 | 0.75 | BAZ2B (0.65) | CFTRBAZ2BKDRUSP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820867-B1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CYSTIC FIBROSIS | FONDAZIONE ST ITALIANO TECNOLOGIA (IT) | 2023-09-13 | — | — | EP | claimed |