SCHEMBL30570936

SCHEMBL30570936

CN1CCCC1COc1ncccn1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CHRNB4 P30926 3/20 0.65
CHRNA3 P32297 3/20 0.65
CHRNB1 P11230 2/20 0.65
CHRNB2 P17787 2/20 0.65
CHRNA4 P43681 2/20 0.65
CHRNB3 Q05901 2/20 0.65
CHRNA1 P02708 1/20 0.62
CHRNA7 P36544 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8436708 1.00 CHRNB4 (0.65) CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4
SCHEMBL29697723 0.81 CHRNB4 (0.63) CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4
SCHEMBL22767884 0.81 CHRNB2 (0.64) CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4
SCHEMBL29924791 0.80 CHRNB4 (0.58) CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4
SCHEMBL29697745 0.80 CHRNB4 (0.58) CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4
SCHEMBL7368969 0.79 CHRNB4 (1.00) CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL8437748 0.78 CHRNB4 (0.97) CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4
SCHEMBL9242858 0.78 CHRNB4 (0.70) CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4
SCHEMBL9243572 0.78 CHRNB4 (0.70) CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4
SCHEMBL6017058 0.78 CHRNB4 (0.49) CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023179196-A1 PREPARATION AND APPLICATION OF WEE1 KINASE INHIBITOR 药雅科技(上海)有限公司 2023-09-28 WO disclosed