Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 3/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.49 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.49 |
| ▸ | CHRNB3 | Q05901 | 2/20 | 0.49 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8436708 | 0.78 | CHRNB4 (0.65) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 | |
| SCHEMBL30570936 | 0.78 | CHRNB4 (0.65) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 | |
| SCHEMBL30825486 | 0.73 | NOS3 (0.50) | — | |
| SCHEMBL22767884 | 0.73 | CHRNB2 (0.64) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 | |
| SCHEMBL5341089 | 0.73 | NOS3 (0.61) | CHRNB4CHRNA3 | |
| SCHEMBL6192460 | 0.72 | CHRNB2 (0.63) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 | |
| SCHEMBL6192462 | 0.72 | CHRNB2 (0.63) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 | |
| SCHEMBL27003329 | 0.71 | CHRNB2 (0.56) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 | |
| SCHEMBL22086716 | 0.70 | CHRNB2 (0.44) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 | |
| SCHEMBL24777038 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7112587-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2006-09-26 | — | — | US | disclosed |