Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30574141 | 0.82 | AVPR1A (0.41) | AVPR1AOXTRCA1CA2PDE3A | |
| SCHEMBL24203802 | 0.81 | ATM (0.40) | AVPR1AOXTR | |
| SCHEMBL24203658 | 0.81 | TDP2 (0.38) | — | |
| SCHEMBL737193 | 0.79 | DPP4 (0.42) | AVPR1AOXTR | |
| SCHEMBL3400246 | 0.79 | AVPR1A (0.42) | AVPR1AOXTRCA1CA2PDE3A | |
| SCHEMBL24204166 | 0.78 | AVPR1A (0.44) | AVPR1AKMT2AOXTR | |
| SCHEMBL11827622 | 0.78 | AVPR1A (0.46) | AVPR1A | |
| SCHEMBL6350679 | 0.77 | SIGMAR1 (0.47) | AVPR1A | |
| SCHEMBL29079064 | 0.74 | AVPR1A (0.39) | AVPR1AOXTR | |
| SCHEMBL12964403 | 0.74 | AVPR1A (0.43) | AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640094-A | Compounds as PRMT1 inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2023-08-25 | — | — | CN | disclosed |