SCHEMBL30575367

SCHEMBL30575367

CC(=O)c1cccc(Nc2ccccc2)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.71
MEN1 O00255 2/20 0.71
AKR1C3 P42330 3/20 0.64
AKR1C2 P52895 3/20 0.64
POLB P06746 1/20 0.61
CYP1A2 P05177 1/20 0.61
AKR1B10 O60218 1/20 0.60
AKR1B1 P15121 1/20 0.60
AKR1C4 P17516 1/20 0.60
AKR1C1 Q04828 1/20 0.60
ALDH1A1 P00352 4/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
NPC1 O15118 2/20 0.59
HPGD P15428 1/20 0.59
ALOX12 P18054 1/20 0.59
RAB9A P51151 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
CREBBP Q92793 1/20 0.58
RHOA P61586 1/20 0.57
MAPT P10636 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5608176 1.00 KMT2A (0.71) KMT2AMEN1AKR1C3AKR1C2POLB
Diphenylamine SCHEMBL9592611 0.88 MAPK13 (0.63) KMT2AMEN1AKR1C3AKR1C2POLB
SCHEMBL5460527 0.86 AKR1C3 (0.67) KMT2AMEN1AKR1C3AKR1C2POLB
SCHEMBL28673562 0.85 KMT2A (0.71) KMT2AMEN1AKR1C3AKR1C2POLB
3-Phenylamino Benzoic Acid SCHEMBL4345076 0.84 RHOA (0.77) KMT2AMEN1AKR1C3AKR1C2ALDH1A1
SCHEMBL11034676 0.83 ALDH1A1 (0.64) KMT2AMEN1AKR1C3AKR1C2ALDH1A1
SCHEMBL4918597 0.83 KMT2A (1.00) KMT2AMEN1POLBCYP1A2ALDH1A1
SCHEMBL7500312 0.83 KMT2A (0.84) KMT2AMEN1POLBALDH1A1SMN1; SMN2
SCHEMBL14982062 0.82 MAPK13 (0.74) KMT2AMEN1AKR1C3AKR1C2ALDH1A1
SCHEMBL4102809 0.82 KMT2A (0.73) KMT2AMEN1POLBCYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116813938-A Conjugated small molecule modified hydrogel and preparation method thereof 金陵科技学院 2023-09-29 CN disclosed