Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.84 |
| ▸ | POLB | P06746 | 2/20 | 0.84 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.79 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.79 |
| ▸ | MEN1 | O00255 | 5/20 | 0.74 |
| ▸ | RAB9A | P51151 | 8/20 | 0.73 |
| ▸ | NPC1 | O15118 | 7/20 | 0.71 |
| ▸ | HPGD | P15428 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.71 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13210704 | 0.94 | KMT2A (0.81) | KMT2APOLBKCNK9KCNK3MEN1 | |
| SCHEMBL6450945 | 0.93 | KMT2A (0.84) | KMT2APOLBKCNK9KCNK3MEN1 | |
| SCHEMBL6454019 | 0.92 | KMT2A (0.78) | KMT2APOLBKCNK9KCNK3MEN1 | |
| SCHEMBL5974770 | 0.91 | KMT2A (0.73) | KMT2APOLBKCNK9KCNK3MEN1 | |
| SCHEMBL23070423 | 0.90 | KMT2A (0.80) | KMT2APOLBKCNK9KCNK3MEN1 | |
| SCHEMBL5974915 | 0.89 | KMT2A (0.69) | KMT2APOLBKCNK9KCNK3MEN1 | |
| SCHEMBL6451496 | 0.89 | KMT2A (0.73) | KMT2APOLBKCNK9KCNK3MEN1 | |
| SCHEMBL2298254 | 0.88 | KCNK3 (1.00) | KMT2APOLBKCNK9KCNK3MEN1 | |
| SCHEMBL23513412 | 0.88 | NPC1 (0.74) | KMT2APOLBKCNK9KCNK3MEN1 | |
| SCHEMBL7745878 | 0.87 | KCNK3 (0.82) | KMT2APOLBKCNK9KCNK3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104739820-A | Small molecule inhibitor and application thereof to inhibiting ornithine decarboxylase (ODC) | UNIV CHINA THREE GORGES CTGU | 2015-07-01 | — | — | CN | disclosed |
| EP-0924202-B1 | Imidazole derivative and medicine comprising the same as active ingredient | SSP CO LTD (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-6071943-A | IMMUNOMODULATORS WHICH SUPPRESS SPECIFIC CYTOKINES, FOR AUTOIMMUNE DISEASES | SSP CO. LTD. (JP) | 2000-06-06 | — | — | US | disclosed |
| EP-0924202-A1 | Imidazole derivative and medicine comprising the same as active ingredient | SSP Co., Ltd. (JP) | 1999-06-23 | — | — | EP | disclosed |