Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30577614 | 0.87 | PDE7A (0.40) | RXFP1L3MBTL1CTDSP1TDP1ADORA2A | |
| SCHEMBL9379712 | 0.82 | LCK (0.40) | RXFP1L3MBTL1CTDSP1TDP1ADORA2A | |
| SCHEMBL30577613 | 0.81 | NQO2 (0.46) | RXFP1L3MBTL1CTDSP1TDP1ADORA2A | |
| SCHEMBL30540493 | 0.77 | MAPT (0.42) | L3MBTL1NPC1KMT2AMAOAACHE | |
| SCHEMBL30577623 | 0.73 | MAPK1 (0.38) | NPC1KDM4EMAPTHPGDERN1 | |
| SCHEMBL30832432 | 0.71 | MAPK1 (0.41) | RXFP1L3MBTL1NPC1KMT2AMEN1 | |
| SCHEMBL7534470 | 0.71 | ALDH1A1 (0.44) | L3MBTL1NPC1KMT2AMAOAACHE | |
| SCHEMBL984339 | 0.71 | MAPK1 (0.41) | RXFP1L3MBTL1NPC1KMT2AMEN1 | |
| SCHEMBL30836700 | 0.70 | MAPK1 (0.43) | L3MBTL1NPC1KMT2AMEN1KDM4E | |
| SCHEMBL23724874 | 0.69 | MAPK1 (0.42) | L3MBTL1NPC1KDM4EMAPTERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023151641-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |