Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | NQO2 | P16083 | 3/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30540544 | 0.88 | MAPK1 (0.37) | MAPK1KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL30540478 | 0.81 | GRM2 (0.39) | LMNA | |
| SCHEMBL30540667 | 0.80 | NQO2 (0.46) | MAPK1KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL30577601 | 0.73 | RXFP1 (0.39) | KDM4EALDH1A1HPGDMAPTERN1 | |
| SCHEMBL31347308 | 0.71 | DYRK1A (0.37) | KDM4EALDH1A1MAPTERN1 | |
| SCHEMBL26107997 | 0.71 | DYRK1A (0.37) | KDM4EALDH1A1MAPTERN1 | |
| SCHEMBL29550479 | 0.70 | MAPK1 (0.41) | MAPK1KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL756526 | 0.70 | MAPK1 (0.41) | MAPK1KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL30540623 | 0.70 | KEAP1 (0.35) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29549946 | 0.70 | KDM4E (0.48) | MAPK1KDM4EALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023151641-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |