Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 8/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 7/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.31 |
| ▸ | IGFBP5 | P24593 | 1/20 | 0.31 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30540487 | 0.80 | CD38 (0.36) | CD38JAK2PDCD1CD274 | |
| SCHEMBL30577598 | 0.78 | JAK2 (0.30) | JAK2JAK3 | |
| SCHEMBL30540576 | 0.77 | KAT2B (0.36) | CD38KAT2B | |
| SCHEMBL30540594 | 0.77 | CD38 (0.36) | CD38ALOX15IGFBP3IGFBP5 | |
| SCHEMBL30540543 | 0.76 | MPO (0.41) | CD38 | |
| SCHEMBL25349795 | 0.75 | CD38 (0.34) | CD38ALOX15IGFBP3IGFBP5 | |
| SCHEMBL30540661 | 0.75 | CD38 (0.34) | CD38ALOX15IGFBP3IGFBP5 | |
| SCHEMBL30540502 | 0.75 | MPO (0.38) | CD38ALOX15IGFBP3IGFBP5 | |
| SCHEMBL30540566 | 0.75 | CD38 (0.35) | CD38ALOX15IGFBP3IGFBP5 | |
| SCHEMBL25348942 | 0.72 | TERT (0.40) | ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023151641-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |