Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30577606 | 0.92 | KLKB1 (0.39) | KLKB1MEN1KMT2ABRPF1DGAT1 | |
| SCHEMBL30540453 | 0.90 | KLKB1 (0.39) | KLKB1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL30577672 | 0.83 | KLKB1 (0.36) | KLKB1MEN1KMT2ABRPF1 | |
| SCHEMBL31115338 | 0.82 | KDM4E (0.36) | KLKB1MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL30540610 | 0.82 | KDM4E (0.36) | KLKB1MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL30540580 | 0.80 | KLKB1 (0.37) | KLKB1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL30577653 | 0.80 | KLKB1 (0.36) | KLKB1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL30540490 | 0.78 | GPR35 (0.40) | KLKB1DGAT1MDM2 | |
| SCHEMBL31115342 | 0.74 | GRM2 (0.35) | KLKB1MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL31115364 | 0.74 | KLKB1 (0.33) | KLKB1MEN1KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023151641-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |