Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26090545 | 0.77 | CA12 (0.46) | KDM4ELMNAMAPTALOX15TSHR | |
| SCHEMBL12659213 | 0.73 | CHRM3 (0.43) | KDM4ELMNAMEN1KMT2AMAPT | |
| SCHEMBL10478110 | 0.72 | LMNA (0.44) | KDM4ELMNAMEN1KMT2AMAPT | |
| SCHEMBL4869840 | 0.71 | TSHR (0.56) | KDM4ELMNAMEN1KMT2AMAPT | |
| SCHEMBL27288846 | 0.71 | LMNA (0.38) | KDM4ELMNAMEN1KMT2AMAPT | |
| SCHEMBL14473542 | 0.70 | TSHR (0.39) | KDM4ELMNAMEN1KMT2AMAPT | |
| SCHEMBL10447298 | 0.69 | TSHR (0.48) | KDM4ELMNAMEN1KMT2AMAPT | |
| SCHEMBL43932 | 0.69 | — | — | |
| SCHEMBL1169301 | 0.69 | TSHR (0.40) | KDM4ELMNAMEN1KMT2AMAPT | |
| SCHEMBL17863914 | 0.68 | DHFR (0.51) | KDM4ELMNAMAPTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116724038-A | Bicyclic compounds | 安力高医药股份有限公司 | 2023-09-08 | — | — | CN | disclosed |