Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | KMO | O15229 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1199986 | 1.00 | L3MBTL1 (0.64) | L3MBTL1TSHRHPGDKDM4EKMO | |
| SCHEMBL10720509 | 0.93 | L3MBTL1 (0.71) | L3MBTL1TSHRHPGDKDM4ERECQL | |
| SCHEMBL4245858 | 0.92 | HPGD (0.74) | L3MBTL1TSHRHPGDKDM4EKMO | |
| SCHEMBL3076585 | 0.89 | TSHR (0.67) | L3MBTL1TSHRHPGDKDM4ERECQL | |
| SCHEMBL16719440 | 0.88 | ACACB (0.58) | L3MBTL1TSHRHPGDKDM4EKMO | |
| SCHEMBL28294867 | 0.88 | HPGD (0.71) | L3MBTL1TSHRHPGDKDM4ERECQL | |
| SCHEMBL3227656 | 0.85 | MEN1 (0.63) | L3MBTL1TSHRHPGDKDM4ERECQL | |
| SCHEMBL7222464 | 0.85 | HPGD (0.78) | L3MBTL1TSHRHPGDKDM4ERECQL | |
| SCHEMBL4248924 | 0.85 | HPGD (0.73) | TSHRHPGDKMOMAPK1ALDH1A1 | |
| SCHEMBL520601 | 0.85 | KDM4E (0.90) | L3MBTL1KDM4ELMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655595-A | 2, 6-piperidinedione derivatives, their preparation and use | 中国人民解放军军事科学院军事医学研究院 | 2023-08-29 | — | — | CN | disclosed |