Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ERN1 | O75460 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10720509 | 0.95 | L3MBTL1 (0.71) | HPGDL3MBTL1KDM4ETSHRRECQL | |
| SCHEMBL1199986 | 0.88 | L3MBTL1 (0.64) | HPGDL3MBTL1KDM4ETSHRRECQL | |
| SCHEMBL30577960 | 0.88 | L3MBTL1 (0.64) | HPGDL3MBTL1KDM4ETSHRRECQL | |
| SCHEMBL3227656 | 0.87 | MEN1 (0.63) | HPGDL3MBTL1KDM4ETSHRRECQL | |
| SCHEMBL3076585 | 0.87 | TSHR (0.67) | HPGDL3MBTL1KDM4ETSHRRECQL | |
| SCHEMBL7069211 | 0.85 | HPGD (0.71) | HPGDL3MBTL1KDM4ETSHRRECQL | |
| SCHEMBL30957421 | 0.85 | HPGD (0.71) | HPGDL3MBTL1KDM4ETSHRRECQL | |
| SCHEMBL6940127 | 0.83 | PHGDH (0.66) | HPGDL3MBTL1KDM4ETSHRRECQL | |
| SCHEMBL1196357 | 0.83 | KDM4E (0.65) | HPGDL3MBTL1KDM4ETSHRRECQL | |
| SCHEMBL520393 | 0.83 | L3MBTL1 (0.62) | HPGDL3MBTL1KDM4ETSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109890821-A | Amino-pyrrolopyrimidine ketone compound and its application method | 艾科尔公司 | 2019-06-14 | — | — | CN | disclosed |