Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | CTSV | O60911 | 5/20 | 0.48 |
| ▸ | CTSL | P07711 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4002579 | 1.00 | AR (0.51) | ARPIN1MAPTCTSVCTSL | |
| SCHEMBL4002405 | 0.84 | L3MBTL1 (0.58) | PIN1MAPTMEN1KMT2ALMNA | |
| SCHEMBL28469094 | 0.83 | CTSV (0.53) | PIN1MAPTCTSVCTSLMEN1 | |
| SCHEMBL4716677 | 0.81 | GAA (0.63) | PIN1MAPTCTSVCTSLNPC1 | |
| SCHEMBL30578466 | 0.81 | GAA (0.63) | PIN1MAPTCTSVCTSLNPC1 | |
| SCHEMBL3919788 | 0.81 | MAPK1 (0.63) | ARMAPTCTSVCTSLMEN1 | |
| SCHEMBL24270838 | 0.80 | SIRT2 (0.51) | ARMAPTCTSVCTSLMEN1 | |
| SCHEMBL29492704 | 0.80 | SIRT2 (0.51) | ARMAPTCTSVCTSLMEN1 | |
| SCHEMBL5579639 | 0.80 | CTSV (0.55) | ARMAPTCTSVCTSLMEN1 | |
| SCHEMBL5580003 | 0.77 | CTSV (0.57) | ARMAPTCTSVCTSLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669725-A | Novel aminopyridine and use thereof in the treatment of cancer | 奥克兰联合服务有限公司 | 2023-08-29 | — | — | CN | disclosed |