SCHEMBL30578807

SCHEMBL30578807

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nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ SLC6A2 P23975 2/20 0.53
▸ CAPN1 P07384 4/20 0.49
▸ CALCRL Q16602 6/20 0.46
▸ CTSB P07858 1/20 0.45
▸ OPRM1 P35372 2/20 0.43
▸ XIAP P98170 1/20 0.40
▸ RAMP1 O60894 1/20 0.40
▸ OPRD1 P41143 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29959682 0.92 SLC6A2 (0.54) SLC6A2CAPN1CALCRLCTSBOPRM1
SCHEMBL29886892 0.87 OPRM1 (0.47) SLC6A2CAPN1OPRM1XIAPOPRD1
SCHEMBL30485547 0.86 SLC6A2 (0.51) SLC6A2CAPN1CALCRLOPRM1XIAP
SCHEMBL29404832 0.86 SLC6A2 (0.48) SLC6A2CAPN1CALCRLXIAPRAMP1
SCHEMBL30525445 0.83 CAPN1 (0.53) SLC6A2CAPN1CALCRLCTSBOPRM1
SCHEMBL30485542 0.83 SLC6A2 (0.48) SLC6A2CAPN1CALCRLCTSBOPRM1
SCHEMBL3253682 0.83 CAPN1 (0.51) SLC6A2CAPN1CTSBOPRM1OPRD1
SCHEMBL3253690 0.83 CAPN1 (0.51) SLC6A2CAPN1CTSBOPRM1OPRD1
SCHEMBL22484305 0.83 XIAP (0.50) SLC6A2CALCRLXIAP
SCHEMBL22484304 0.83 XIAP (0.50) SLC6A2CALCRLXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146066-A1 STOICHIOMETRIC GAS VESICLE EXPRESSION SYSTEM AND RELATED CONSTRUCTS, GENETIC CIRCUITS, VECTORS, CELLS, HOSTS, COMPOSITIONS, METHODS AND SYSTEMS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2026-05-28 — — US disclosed
US-20250230446-A1 GAS VESICLE EXPRESSION SYSTEMS, GAS VESICLE CONSTRUCTS AND RELATED GENETIC CIRCUITS, VECTORS, MAMMALIAN CELLS, HOSTS, COMPOSITIONS, METHODS AND SYSTEMS CALIFORNIA INSTITUTE OF TECHNOLOGY 2025-07-17 — — US disclosed
US-12241069-B2 Gas vesicle expression systems, gas vesicle constructs and related genetic circuits, vectors, mammalian cells, hosts, compositions, methods and systems CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2025-03-04 — — US disclosed
US-20230357780-A1 GAS VESICLE EXPRESSION SYSTEMS, GAS VESICLE CONSTRUCTS AND RELATED GENETIC CIRCUITS, VECTORS, MAMMALIAN CELLS, HOSTS, COMPOSITIONS, METHODS AND SYSTEMS CALIFORNIA INSTITUTE OF TECHNOLOGY 2023-11-09 — — US disclosed
US-11761008-B2 Gas vesicle expression systems, gas vesicle constructs and related genetic circuits, vectors, mammalian cells, hosts, compositions, methods and systems CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-09-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146066-A1 STOICHIOMETRIC GAS VESICLE EXPRESSION SYSTEM AND RELATED CONSTRUCTS, GENETIC CIRCUITS, VECTORS, CELLS, HOSTS, COMPOSITIONS, METHODS AND SYSTEMS EXOSC4, TIA1, GNAI2 SLC6A2 3234/4885CAPN1 1873/4885CALCRL 4198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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