Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.49 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
| ▸ | NTSR2 | O95665 | 6/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 6/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22484304 | 1.00 | XIAP (0.50) | XIAPAGTR2AGTR1CALCRLREN | |
| SCHEMBL25524242 | 0.95 | AGTR2 (0.50) | XIAPAGTR2AGTR1CALCRLREN | |
| SCHEMBL25524189 | 0.94 | XIAP (0.53) | XIAPAGTR2AGTR1CALCRLREN | |
| SCHEMBL29401292 | 0.92 | XIAP (0.47) | XIAPAGTR2AGTR1CALCRLNTSR2 | |
| SCHEMBL24217628 | 0.87 | CMA1 (0.44) | XIAPAGTR2AGTR1CALCRLSLC6A2 | |
| SCHEMBL24217630 | 0.87 | CMA1 (0.44) | XIAPAGTR2AGTR1CALCRLSLC6A2 | |
| SCHEMBL30067143 | 0.84 | NTSR2 (0.51) | RENNTSR2NTSR1SORT1 | |
| SCHEMBL29680178 | 0.84 | CALCRL (0.45) | XIAPCALCRLNTSR2NTSR1SORT1 | |
| SCHEMBL29454515 | 0.84 | XIAP (0.49) | XIAPCALCRLRENSLC6A2 | |
| SCHEMBL29454468 | 0.84 | XIAP (0.49) | XIAPCALCRLRENSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230241026-A1 | NOVEL DRUG-CONTROLLED SYSTEMS AND USES THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2023-08-03 | — | — | US | disclosed |
| US-11660288-B2 | Drug-controlled systems and uses thereof | TRUSTEES OF BOSTON UNIVERSITY (US) | 2023-05-30 | — | — | US | disclosed |
| US-20230159600-A1 | REGULATED SYNTHETIC GENE EXPRESSION SYSTEMS | TRUSTEES OF BOSTON UNIVERSITY (US) | 2023-05-25 | — | — | US | disclosed |
| US-11530246-B2 | Regulated synthetic gene expression systems | TRUSTEES OF BOSTON UNIVERSITY (US) | 2022-12-20 | — | — | US | disclosed |
| US-11059864-B2 | Chimeric antigen receptor (CAR) modulation | TRUSTEES OF BOSTON UNIVERSITY (US) | 2021-07-13 | — | — | US | disclosed |
| US-20200377564-A1 | REGULATED SYNTHETIC GENE EXPRESSION SYSTEMS | TRUSTEES OF BOSTON UNIVERSITY (US) | 2020-12-03 | — | — | US | disclosed |
| US-20200308234-A1 | CHIMERIC ANTIGEN RECEPTOR (CAR) MODULATION | TRUSTEES OF BOSTON UNIVERSITY (US) | 2020-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11059864-B2 | Chimeric antigen receptor (CAR) modulation | HAVCR2, CPB1, CTRL | XIAP 1236/4885AGTR2 957/4885AGTR1 587/4885 |
| US-20230159600-A1 | REGULATED SYNTHETIC GENE EXPRESSION SYSTEMS | SRRT, BPTF, MYCBP | XIAP 1847/4885AGTR2 3520/4885AGTR1 3706/4885 |
| US-11660288-B2 | Drug-controlled systems and uses thereof | ATF4, MRPL21, SARS1 | XIAP 166/4885AGTR2 1842/4885AGTR1 1890/4885 |
| US-20230241026-A1 | NOVEL DRUG-CONTROLLED SYSTEMS AND USES THEREOF | ATF4, MRPL21, TMPRSS2 | XIAP 201/4885AGTR2 1332/4885AGTR1 1430/4885 |
| US-11530246-B2 | Regulated synthetic gene expression systems | SRRT, BPTF, MYCBP | XIAP 1847/4885AGTR2 3520/4885AGTR1 3706/4885 |
| US-20200308234-A1 | CHIMERIC ANTIGEN RECEPTOR (CAR) MODULATION | HAVCR2, CPB1, CTRL | XIAP 1236/4885AGTR2 957/4885AGTR1 587/4885 |
| US-20200377564-A1 | REGULATED SYNTHETIC GENE EXPRESSION SYSTEMS | SRRT, BPTF, MYCBP | XIAP 1847/4885AGTR2 3520/4885AGTR1 3706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.