Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR2 | P30874 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 3/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22074898 | 1.00 | SSTR2 (0.34) | SSTR2CCNT1CDK9ERN1FGFR3 | |
| SCHEMBL30579175 | 0.89 | CCNT1 (0.33) | CCNT1CDK9ERN1 | |
| SCHEMBL22075307 | 0.89 | CCNT1 (0.33) | CCNT1CDK9ERN1 | |
| SCHEMBL22074867 | 0.87 | SLC6A4 (0.42) | FGFR3KDR | |
| SCHEMBL30579106 | 0.87 | SLC6A4 (0.42) | FGFR3KDR | |
| SCHEMBL22075164 | 0.83 | FGFR3 (0.33) | FGFR3KDR | |
| SCHEMBL25084761 | 0.81 | TGFBR1 (0.38) | CCNT1CDK9ERN1KDR | |
| SCHEMBL30155961 | 0.81 | TGFBR1 (0.38) | CCNT1CDK9ERN1KDR | |
| SCHEMBL22074936 | 0.80 | SSTR2 (0.36) | SSTR2CCNT1FGFR3KDR | |
| SCHEMBL30579154 | 0.80 | SSTR2 (0.36) | SSTR2CCNT1FGFR3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11730720-B2 | ALK5 inhibitors | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2023-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11730720-B2 | ALK5 inhibitors | ALK, ACVR1, ACVRL1 | SSTR2 1373/4885CCNT1 4564/4885CDK9 1029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.