Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 0.73 |
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | DRD2 | P14416 | 1/20 | 0.64 |
| ▸ | HTR1D | P28221 | 1/20 | 0.64 |
| ▸ | HTR1B | P28222 | 1/20 | 0.64 |
| ▸ | HTR1F | P30939 | 1/20 | 0.64 |
| ▸ | HTR7 | P34969 | 1/20 | 0.64 |
| ▸ | DRD3 | P35462 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13137678 | 1.00 | HTR6 (0.73) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL2132873 | 0.88 | HTR6 (0.72) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL946691 | 0.86 | HTR6 (0.75) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL7902124 | 0.84 | HTR6 (0.73) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL946710 | 0.84 | HTR6 (0.73) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL8689013 | 0.84 | HTR6 (0.68) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL7494457 | 0.82 | HTR6 (0.54) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL7894537 | 0.82 | HTR6 (0.74) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL3624652 | 0.82 | HTR6 (0.71) | HTR6HTR1ADRD2HTR1DHTR1B | |
| SCHEMBL16704081 | 0.82 | HTR6 (0.69) | HTR6HTR1ADRD2HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110831600-B | Indole AHR inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2023-10-17 | — | — | CN | disclosed |