Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 11/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645020 | 0.90 | CSNK1E (0.45) | RIPK3NR3C2IRAK4MAPK14CSNK1D | |
| SCHEMBL30579563 | 0.90 | CSNK1E (0.45) | RIPK3NR3C2IRAK4MAPK14CSNK1D | |
| SCHEMBL24554177 | 0.90 | CSNK1E (0.45) | RIPK3NR3C2IRAK4MAPK14CSNK1D | |
| SCHEMBL26645749 | 0.90 | CSNK1E (0.45) | RIPK3NR3C2IRAK4MAPK14CSNK1D | |
| SCHEMBL29683274 | 0.88 | NR3C2 (0.44) | NR3C2MAPK14CSNK1DCSNK1EMAPK13 | |
| SCHEMBL24554150 | 0.88 | NR3C2 (0.44) | NR3C2MAPK14CSNK1DCSNK1EMAPK13 | |
| SCHEMBL31680474 | 0.88 | RIPK3 (0.43) | RIPK3NR3C2IRAK4MAPK14CSNK1D | |
| SCHEMBL24554417 | 0.87 | MAPK14 (0.42) | RIPK3NR3C2MAPK14CSNK1DCSNK1E | |
| SCHEMBL29683240 | 0.87 | MAPK14 (0.42) | RIPK3NR3C2MAPK14CSNK1DCSNK1E | |
| SCHEMBL25223642 | 0.87 | NR3C2 (0.46) | NR3C2MAPK14CSNK1DCSNK1EMAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192699-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | Gritscience Biopharmaceuticals Co., Ltd. (CN) | 2023-06-22 | — | — | US | disclosed |
| CN-115335057-A | Method for inhibiting casein kinase | 北京原基华毅生物科技有限公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-115298183-A | Compounds as casein kinase inhibitors | 北京原基华毅生物科技有限公司 | 2022-11-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192699-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | CSNK2A3, CSNK1A1, CSNK1G3 | RIPK3 1228/4885NR3C2 1031/4885IRAK4 713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.