Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | YES1 | P07947 | 1/20 | 0.33 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26106044 | 1.00 | CCNT1 (0.38) | CCNT1CDK9KDM4EALDH1A1LMNA | |
| SCHEMBL30582620 | 0.89 | RIPK2 (0.40) | CCNT1CDK9RIPK2LRRK2EIF2AK3 | |
| SCHEMBL26109630 | 0.89 | RIPK2 (0.40) | CCNT1CDK9RIPK2LRRK2EIF2AK3 | |
| SCHEMBL30582544 | 0.89 | SRC (0.44) | CCNT1CDK9KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL26108026 | 0.89 | SRC (0.44) | CCNT1CDK9KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30582578 | 0.87 | KIT (0.35) | CCNT1CDK9BTKLRRK2SRC | |
| SCHEMBL26106140 | 0.87 | KIT (0.35) | CCNT1CDK9BTKLRRK2SRC | |
| SCHEMBL30582633 | 0.87 | CCNT1 (0.34) | CCNT1CDK9LRRK2SRCKDR | |
| SCHEMBL26106109 | 0.87 | CCNT1 (0.34) | CCNT1CDK9LRRK2SRCKDR | |
| SCHEMBL30582625 | 0.86 | KCNH2 (0.39) | SRCKDRABL1EGFRLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4499616-A1 | SPIROBICYCLIC COMPOUNDS | Acerand Therapeutics (Hong Kong) Limited (HK) | 2025-02-05 | — | — | EP | disclosed |
| CN-119013260-A | Spirobicyclic compounds | 优领医药科技(香港)有限公司 | 2024-11-22 | — | — | CN | disclosed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |