Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 17/20 | 0.47 |
| ▸ | EGFR | P00533 | 12/20 | 0.47 |
| ▸ | ABL1 | P00519 | 11/20 | 0.47 |
| ▸ | ABL2 | P42684 | 10/20 | 0.47 |
| ▸ | CDK1 | P06493 | 2/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | HCK | P08631 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | LYN | P07948 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26109072 | 1.00 | SRC (0.47) | SRCEGFRABL1ABL2CDK1 | |
| SCHEMBL30582544 | 0.89 | SRC (0.44) | SRCEGFRABL1ABL2EPHB4 | |
| SCHEMBL26108026 | 0.89 | SRC (0.44) | SRCEGFRABL1ABL2EPHB4 | |
| SCHEMBL30582620 | 0.88 | RIPK2 (0.40) | SRCEGFRABL1ABL2PIK3CD | |
| SCHEMBL26109630 | 0.88 | RIPK2 (0.40) | SRCEGFRABL1ABL2PIK3CD | |
| SCHEMBL26109317 | 0.85 | SRC (0.41) | SRCEGFRABL1ABL2CDK1 | |
| SCHEMBL30582499 | 0.84 | ITK (0.49) | EGFR | |
| SCHEMBL30582596 | 0.84 | SRC (0.52) | SRCEGFRABL1ABL2CDK1 | |
| SCHEMBL26108199 | 0.84 | SRC (0.52) | SRCEGFRABL1ABL2CDK1 | |
| SCHEMBL26107050 | 0.84 | LCK (0.40) | SRCEGFRKDRLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4499616-A1 | SPIROBICYCLIC COMPOUNDS | Acerand Therapeutics (Hong Kong) Limited (HK) | 2025-02-05 | — | — | EP | disclosed |
| CN-119013260-A | Spirobicyclic compounds | 优领医药科技(香港)有限公司 | 2024-11-22 | — | — | CN | disclosed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |