Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 7/20 | 0.33 |
| ▸ | LCK | P06239 | 3/20 | 0.33 |
| ▸ | TEK | Q02763 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | CSK | P41240 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ABL2 | P42684 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30582593 | 1.00 | KCNH2 (0.34) | KCNH2PRKD3SRCLCKTEK | |
| SCHEMBL26108928 | 1.00 | KCNH2 (0.34) | KCNH2PRKD3SRCLCKTEK | |
| SCHEMBL30582625 | 0.89 | KCNH2 (0.39) | KCNH2SRCLCKTEKKDR | |
| SCHEMBL26106994 | 0.89 | KCNH2 (0.39) | KCNH2SRCLCKTEKKDR | |
| SCHEMBL26108721 | 0.86 | KCNH2 (0.33) | KCNH2PRKD3 | |
| SCHEMBL31219399 | 0.86 | MAP4K4 (0.33) | SRCLCKTEKKDRABL1 | |
| SCHEMBL30582523 | 0.85 | ITK (0.43) | EGFR | |
| SCHEMBL26104650 | 0.85 | ITK (0.43) | EGFR | |
| SCHEMBL30582602 | 0.85 | DYRK1A (0.33) | KCNH2SRCLCKTEKKDR | |
| SCHEMBL26106237 | 0.85 | DYRK1A (0.33) | KCNH2SRCLCKTEKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4499616-A1 | SPIROBICYCLIC COMPOUNDS | Acerand Therapeutics (Hong Kong) Limited (HK) | 2025-02-05 | — | — | EP | disclosed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |