Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.33 |
| ▸ | METTL3 | Q86U44 | 3/20 | 0.33 |
| ▸ | SRC | P12931 | 8/20 | 0.33 |
| ▸ | LCK | P06239 | 2/20 | 0.33 |
| ▸ | TEK | Q02763 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 3/20 | 0.32 |
| ▸ | RET | P07949 | 3/20 | 0.32 |
| ▸ | EGFR | P00533 | 3/20 | 0.32 |
| ▸ | ABL2 | P42684 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | FGR | P09769 | 1/20 | 0.31 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.31 |
| ▸ | TXK | P42681 | 1/20 | 0.31 |
| ▸ | FRK | P42685 | 1/20 | 0.31 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | MTOR | P42345 | 2/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26105963 | 0.86 | CCNT1 (0.34) | PRMT5METTL3SRCABL1RET | |
| SCHEMBL30582608 | 0.86 | CCNT1 (0.34) | PRMT5METTL3SRCABL1RET | |
| SCHEMBL30582593 | 0.86 | KCNH2 (0.34) | SRCLCKTEKABL1EGFR | |
| SCHEMBL30582590 | 0.86 | KCNH2 (0.34) | SRCLCKTEKABL1EGFR | |
| SCHEMBL26108928 | 0.86 | KCNH2 (0.34) | SRCLCKTEKABL1EGFR | |
| SCHEMBL31219432 | 0.85 | RET (0.33) | PRMT5METTL3RETLRRK2 | |
| SCHEMBL31219342 | 0.84 | ITK (0.40) | EGFR | |
| SCHEMBL30582605 | 0.84 | CCNT1 (0.38) | SRCLCKTEKABL1RET | |
| SCHEMBL26106044 | 0.84 | CCNT1 (0.38) | SRCLCKTEKABL1RET | |
| SCHEMBL30582601 | 0.83 | PIK3CD (0.40) | SRCABL1RETEGFRLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013260-A | Spirobicyclic compounds | 优领医药科技(香港)有限公司 | 2024-11-22 | — | — | CN | disclosed |