Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 7/20 | 0.46 |
| ▸ | SRC | P12931 | 6/20 | 0.45 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | ABL1 | P00519 | 5/20 | 0.39 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | ABL2 | P42684 | 2/20 | 0.39 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26109562 | 0.90 | RIPK2 (0.47) | RIPK2SRCKDRABL1EGFR | |
| SCHEMBL26104736 | 0.87 | BTK (0.49) | RIPK2SRCRETABL1EGFR | |
| SCHEMBL30582611 | 0.87 | BTK (0.49) | RIPK2SRCRETABL1EGFR | |
| SCHEMBL30582631 | 0.83 | PDE2A (0.43) | RIPK2SRCPDE2ARETKDR | |
| SCHEMBL26107090 | 0.83 | RIPK2 (0.49) | RIPK2SRCKDRABL1EGFR | |
| SCHEMBL30582549 | 0.83 | RIPK2 (0.49) | RIPK2SRCKDRABL1EGFR | |
| SCHEMBL26587463 | 0.74 | RET (0.41) | RETKDREGFRBTK | |
| SCHEMBL26109460 | 0.72 | RIPK2 (0.43) | RIPK2SRCRETABL1EGFR | |
| SCHEMBL30582582 | 0.71 | SRC (0.43) | SRCRETKDRABL1EGFR | |
| SCHEMBL26105238 | 0.71 | SRC (0.43) | SRCRETKDRABL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4499616-A1 | SPIROBICYCLIC COMPOUNDS | Acerand Therapeutics (Hong Kong) Limited (HK) | 2025-02-05 | — | — | EP | disclosed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |