SCHEMBL30583100

SCHEMBL30583100

COc1cc(OC)c(Cl)c(B2OC(C)(C)C(C)(C)O2)c1Cl

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
EGFR P00533 2/20 0.34
CSF1R P07333 1/20 0.34
GAA P10253 1/20 0.33
LPL P06858 2/20 0.31
LIPG Q9Y5X9 2/20 0.31
P2RX7 Q99572 1/20 0.31
SNCA P37840 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28116992 0.82
SCHEMBL31466833 0.81 CSF1R (0.37) EGFRCSF1RLPLLIPG
SCHEMBL23043995 0.80 SMN1; SMN2 (0.39) EGFRCSF1RLPLLIPG
SCHEMBL263916 0.79 EGFR (0.40) EGFRCSF1R
SCHEMBL15796063 0.78 LPL (0.37) EGFRCSF1RLPLLIPGP2RX7
SCHEMBL16655541 0.77 CSF1R (0.37) EGFRCSF1RGAALPLLIPG
SCHEMBL20899463 0.77 HTR2A (0.35) EGFRCSF1RLPLLIPG
SCHEMBL31048110 0.77 EGFR (0.36) EGFRCSF1RGAA
SCHEMBL1506041 0.77 EGFR (0.36) EGFRCSF1RGAA
SCHEMBL20075283 0.77 LPL (0.35) LPLLIPGP2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116813526-A Isoindolinone compound, preparation method and application thereof 四川省医学科学院·四川省人民医院 2023-09-29 CN disclosed