SCHEMBL30583141

SCHEMBL30583141

Nc1nc(OCC2CCC(=O)N2)c2nc[nH]c2n1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 17/20 0.41
IRAK1 P51617 1/20 0.40
CDK1 P06493 2/20 0.39
CCNB1 P14635 2/20 0.39
CCNA2 P20248 2/20 0.39
CDK2 P24941 2/20 0.39
CCNA1 P78396 2/20 0.39
KCNH2 Q12809 1/20 0.39
CCNB2 O95067 1/20 0.39
MAPK3 P27361 1/20 0.39
CLK1 P49759 1/20 0.39
CDK5 Q00535 1/20 0.39
PIN1 Q13526 1/20 0.39
CCNB3 Q8WWL7 1/20 0.39
MAP3K5 Q99683 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4556489 1.00 IRAK4 (0.41) IRAK4IRAK1CDK1CCNB1CCNA2
SCHEMBL13075175 0.84 IRAK4 (0.48) IRAK4IRAK1KCNH2
SCHEMBL7982278 0.81 CDK1 (0.62) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL7981110 0.81 CDK1 (0.62) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL8826249 0.79 CDK2 (0.56) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL6266040 0.77 CDK2 (0.64) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL29385503 0.76 CDK2 (0.64) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL4402025 0.76 CDK2 (0.64) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL6267556 0.72 CDK2 (0.67) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL7984872 0.71 CDK2 (0.42) CDK1CCNB1CCNA2CDK2CCNA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 EP disclosed