Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 17/20 | 0.62 |
| ▸ | CCNB1 | P14635 | 17/20 | 0.62 |
| ▸ | CCNA2 | P20248 | 16/20 | 0.62 |
| ▸ | CDK2 | P24941 | 16/20 | 0.62 |
| ▸ | CCNA1 | P78396 | 16/20 | 0.62 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.61 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.61 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.61 |
| ▸ | CLK1 | P49759 | 1/20 | 0.61 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.61 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.61 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.61 |
| ▸ | MGMT | P16455 | 9/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981110 | 1.00 | CDK1 (0.62) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL30583141 | 0.81 | IRAK4 (0.41) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL4556489 | 0.81 | IRAK4 (0.41) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL6266042 | 0.77 | CDK2 (1.00) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL3462331 | 0.76 | CDK2 (1.00) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL8069356 | 0.73 | CDK1 (0.69) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL6267558 | 0.72 | CDK1 (1.00) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL13075175 | 0.72 | IRAK4 (0.48) | — | |
| SCHEMBL7984874 | 0.71 | CDK1 (0.66) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL8618498 | 0.70 | CDK1 (0.77) | CDK1CCNB1CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303618-B1 | ADMINISTERING PURINE COMPOUND WHICH INHIBITS CYCLIC DEPENDENT KINASE ACTIVITY FOR THERAPY OF TUMOR OR OTHER CELL PROLIFERATION DISORDER | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2001-10-16 | — | — | US | disclosed |