SCHEMBL30583142

SCHEMBL30583142

CCSCC[C@H](N)[C@H](O)C(=O)N[C@@H](C)c1cccc2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 20/20 1.00
METAP1 P53582 15/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4317564 0.81 METAP2 (0.68) METAP2METAP1
SCHEMBL6477355 0.79 METAP2 (1.00) METAP2METAP1
SCHEMBL6476864 0.78 METAP2 (0.72) METAP2METAP1
SCHEMBL7319273 0.78 METAP2 (0.72) METAP2METAP1
SCHEMBL4317560 0.77 METAP2 (0.66) METAP2METAP1
SCHEMBL6485389 0.77 METAP2 (0.69) METAP2METAP1
SCHEMBL6476486 0.76 METAP2 (0.68) METAP2METAP1
SCHEMBL7355989 0.75 METAP2 (0.77) METAP2METAP1
SCHEMBL7361408 0.75 METAP2 (0.77) METAP2METAP1
SCHEMBL7355173 0.75 METAP2 (0.77) METAP2METAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 EP disclosed