SCHEMBL4317564

SCHEMBL4317564

CCSCCC(N)C(O)C(=O)C(C(N)=O)c1cccc2ccccc12

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 20/20 0.68
METAP1 P53582 14/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30583142 0.81 METAP2 (1.00) METAP2METAP1
SCHEMBL6477355 0.75 METAP2 (1.00) METAP2METAP1
SCHEMBL7319273 0.74 METAP2 (0.72) METAP2METAP1
SCHEMBL6476864 0.74 METAP2 (0.72) METAP2METAP1
SCHEMBL6939035 0.74 METAP2 (0.64) METAP2METAP1
SCHEMBL4317560 0.73 METAP2 (0.66) METAP2METAP1
SCHEMBL6485389 0.73 METAP2 (0.69) METAP2METAP1
SCHEMBL6476486 0.72 METAP2 (0.68) METAP2METAP1
SCHEMBL7308705 0.71 METAP2 (0.56) METAP2METAP1
SCHEMBL6935848 0.69 METAP2 (0.53) METAP2METAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10877035-B2 Advanced drug development and manufacturing ICAGEN, LLC (US) 2020-12-29 US disclosed
US-20150309021-A1 Advanced Drug Development and Manufacturing LOS ALAMOS NATIONAL SECURITY, LLC 2015-10-29 US disclosed
EP-2511844-B1 X-ray microscope XRPRO SCIENCES INC (US) 2015-08-12 EP disclosed
EP-2511844-A2 Advanced drug development and manufacturing Los Alamos National Security, LLC (US) 2012-10-17 EP disclosed
EP-2084519-B1 X-RAY FLUORESCENCE ANALYSIS METHOD LOS ALAMOS NAT SECURITY LLC (US) 2012-08-01 EP disclosed
EP-2084519-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING Los Alamos National Security, LLC (US) 2009-08-05 EP disclosed
WO-2008127291-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-10-23 WO disclosed
US-20080220441-A1 Advanced drug development and manufacturing THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2008-09-11 US disclosed