Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | SLC26A3 | P40879 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26662515 | 1.00 | PIK3CA (0.32) | PIK3CANOTUMSLC26A3 | |
| SCHEMBL31035393 | 0.81 | ALDH1A1 (0.33) | — | |
| SCHEMBL23887049 | 0.78 | DDR1 (0.39) | — | |
| SCHEMBL23887306 | 0.70 | PTPN1 (0.34) | — | |
| SCHEMBL30564392 | 0.69 | KMT2A (0.31) | — | |
| SCHEMBL12535480 | 0.66 | GABRB3 (0.40) | NOTUM | |
| SCHEMBL30307533 | 0.66 | DDR1 (0.40) | NOTUM | |
| SCHEMBL23887067 | 0.66 | DDR1 (0.40) | NOTUM | |
| SCHEMBL28631552 | 0.65 | ALDH1A1 (0.47) | — | |
| SCHEMBL28792357 | 0.64 | MAOB (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4514784-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | Petra Pharma Corporation (US) | 2025-03-05 | — | — | EP | disclosed |
| CN-119301106-A | Allosteric benzopyrone inhibitors of phosphoinositide 3-kinase (PI 3K) for the treatment of disease | 佩特拉制药公司 | 2025-01-10 | — | — | CN | disclosed |
| WO-2023212693-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | PETRA PHARMA CORPORATION (US) | 2023-11-02 | — | — | WO | disclosed |