Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | S100A4 | P26447 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29250710 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HIF1AMAPTHSD17B10KMT2A | |
| SCHEMBL29126851 | 0.77 | KMT2A (0.47) | ALDH1A1MAPTHSD17B10KMT2AOPRK1 | |
| SCHEMBL31119106 | 0.77 | PIK3CA (0.46) | ALDH1A1HIF1AMAPTHSD17B10KMT2A | |
| SCHEMBL2648750 | 0.77 | PIK3CA (0.46) | ALDH1A1HIF1AMAPTHSD17B10KMT2A | |
| SCHEMBL26697038 | 0.76 | CLK1 (0.59) | MAPTKMT2AOPRK1NPBWR1CCNB2 | |
| SCHEMBL30716301 | 0.76 | CLK1 (0.59) | MAPTKMT2AOPRK1NPBWR1CCNB2 | |
| SCHEMBL16513230 | 0.75 | KMT2A (0.45) | ALDH1A1HIF1AMAPTHSD17B10KMT2A | |
| SCHEMBL30584572 | 0.75 | KMT2A (0.45) | ALDH1A1HIF1AMAPTHSD17B10KMT2A | |
| SCHEMBL30584582 | 0.75 | PIN1 (0.56) | ALDH1A1HIF1AMAPTKMT2APIN1 | |
| SCHEMBL29250669 | 0.75 | PIN1 (0.56) | ALDH1A1HIF1AMAPTKMT2APIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685583-A | Pyrimidine compounds, compositions and pharmaceutical uses thereof | 缆图药品公司 | 2023-09-01 | — | — | CN | disclosed |