SCHEMBL30584795

SCHEMBL30584795

Cc1ccc(CN2CCC(CNC(=O)C3CCN(c4nc(-c5cccc(O)c5)no4)CC3)C2)cc1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CCR5 P51681 1/20 0.52
▸ TP53 P04637 6/20 0.47
▸ USP2 O75604 1/20 0.47
▸ LMNA P02545 1/20 0.47
▸ TSHR P16473 1/20 0.47
▸ MAPT P10636 4/20 0.45
▸ THRB P10828 1/20 0.45
▸ CHRM4 P08173 2/20 0.43
▸ MEN1 O00255 1/20 0.42
▸ KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25434022 1.00 CCR5 (0.52) CCR5TP53USP2LMNATSHR
SCHEMBL31546362 0.94 CCR5 (0.54) CCR5TP53USP2LMNATSHR
SCHEMBL25433137 0.91 CCR5 (0.53) CCR5TP53USP2LMNATSHR
SCHEMBL30584865 0.90 MEN1 (0.53) CCR5TP53LMNATSHRMAPT
SCHEMBL25439353 0.90 MEN1 (0.53) CCR5TP53LMNATSHRMAPT
Formic Acid SCHEMBL25433807 0.90 CCR5 (0.50) CCR5TP53USP2LMNATSHR
Formic Acid SCHEMBL30584692 0.90 CCR5 (0.50) CCR5TP53USP2LMNATSHR
SCHEMBL30585036 0.90 MAPT (0.52) CCR5TP53USP2LMNATSHR
Formic Acid SCHEMBL25433503 0.88 MEN1 (0.51) CCR5TP53LMNATSHRMAPT
Formic Acid SCHEMBL30584841 0.88 MEN1 (0.51) CCR5TP53LMNATSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 — — EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 CCR5 3713/4885TP53 54/4885USP2 2798/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 CCR5 3713/4885TP53 54/4885USP2 2798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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