SCHEMBL30585036

SCHEMBL30585036

Cc1ccc(CN2CCC(CNC(=O)C3CCN(c4nc(-c5cccc(C#N)c5)no4)CC3)C2)cc1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.52
▸ CCR5 P51681 1/20 0.50
▸ MCHR1 Q99705 4/20 0.49
▸ CHRM4 P08173 2/20 0.48
▸ TP53 P04637 2/20 0.45
▸ THRB P10828 1/20 0.45
▸ USP2 O75604 1/20 0.45
▸ LMNA P02545 1/20 0.45
▸ TSHR P16473 1/20 0.45
▸ HRH3 Q9Y5N1 3/20 0.45
▸ ACHE P22303 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30584823 0.91 ACHE (0.51) MAPTCCR5CHRM4TP53USP2
SCHEMBL31546362 0.91 CCR5 (0.54) MAPTCCR5CHRM4TP53THRB
SCHEMBL25434022 0.90 CCR5 (0.52) MAPTCCR5CHRM4TP53THRB
SCHEMBL30584795 0.90 CCR5 (0.52) MAPTCCR5CHRM4TP53THRB
SCHEMBL25439353 0.88 MEN1 (0.53) MAPTCCR5CHRM4TP53LMNA
SCHEMBL30584865 0.88 MEN1 (0.53) MAPTCCR5CHRM4TP53LMNA
Formic Acid SCHEMBL25433807 0.87 CCR5 (0.50) MAPTCCR5TP53USP2LMNA
Formic Acid SCHEMBL30584692 0.87 CCR5 (0.50) MAPTCCR5TP53USP2LMNA
Formic Acid SCHEMBL25433503 0.85 MEN1 (0.51) MAPTCCR5CHRM4TP53LMNA
Formic Acid SCHEMBL30584841 0.85 MEN1 (0.51) MAPTCCR5CHRM4TP53LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 — — EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 MAPT 2999/4885CCR5 3713/4885MCHR1 3470/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 MAPT 2999/4885CCR5 3713/4885MCHR1 3470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback