SCHEMBL30584892

SCHEMBL30584892

O=C(NCCCN1CCC(Cc2ccccc2)CC1)C1CCN(c2nc(-c3ccc(OC(F)F)cc3)no2)CC1

nearest known ligand 0.63

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.59
▸ KMT2A Q03164 2/20 0.59
▸ SMN1; SMN2 Q16637 2/20 0.58
▸ ALDH1A1 P00352 1/20 0.58
▸ LMNA P02545 1/20 0.58
▸ TP53 P04637 1/20 0.58
▸ TSHR P16473 1/20 0.58
▸ HTT P42858 1/20 0.58
▸ CHRM4 P08173 1/20 0.55
▸ MAPT P10636 1/20 0.53
▸ CYP2D6 P10635 1/20 0.53
▸ CYP2C19 P33261 1/20 0.53
▸ SLC6A2 P23975 4/20 0.51
▸ SLC6A4 P31645 3/20 0.51
▸ SLC6A3 Q01959 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25433518 0.91 MEN1 (0.56) MEN1KMT2ASMN1; SMN2ALDH1A1LMNA
Formic Acid SCHEMBL31546365 0.88 MEN1 (0.68) MEN1KMT2ASMN1; SMN2ALDH1A1LMNA
Formic Acid SCHEMBL30584790 0.88 MEN1 (0.56) MEN1KMT2ASMN1; SMN2ALDH1A1LMNA
Formic Acid SCHEMBL31546374 0.84 CCR3 (0.56) MEN1KMT2ASMN1; SMN2ALDH1A1LMNA
SCHEMBL30584948 0.82 LMNA (0.52) MEN1KMT2ASMN1; SMN2ALDH1A1LMNA
SCHEMBL30584775 0.81 LMNA (0.49) MEN1KMT2ASMN1; SMN2ALDH1A1LMNA
SCHEMBL31546418 0.81 LMNA (0.72) MEN1KMT2ASMN1; SMN2ALDH1A1LMNA
SCHEMBL25434754 0.80 MEN1 (0.56) MEN1KMT2ASMN1; SMN2ALDH1A1LMNA
SCHEMBL31546358 0.78 MEN1 (0.73) MEN1KMT2ASMN1; SMN2ALDH1A1LMNA
SCHEMBL25402120 0.77 MEN1 (0.52) MEN1KMT2ASMN1; SMN2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 — — EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 MEN1 1569/4885KMT2A 1404/4885SMN1; SMN2 3115/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 MEN1 1569/4885KMT2A 1404/4885SMN1; SMN2 3115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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