SCHEMBL30584948

SCHEMBL30584948

O=C(NCCCN1CCC(Cc2ccccc2F)CC1)N1CCN(c2nc(-c3ccc(OC(F)F)cc3)no2)CC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 5/20 0.52
▸ TSHR P16473 4/20 0.52
▸ HTT P42858 3/20 0.52
▸ SMN1; SMN2 Q16637 3/20 0.52
▸ TP53 P04637 2/20 0.52
▸ ALDH1A1 P00352 1/20 0.52
▸ GAA P10253 2/20 0.48
▸ MAPT P10636 3/20 0.46
▸ THRB P10828 1/20 0.46
▸ MEN1 O00255 2/20 0.46
▸ KMT2A Q03164 2/20 0.46
▸ KDM4E B2RXH2 1/20 0.43
▸ POLB P06746 1/20 0.43
▸ CCR3 P51677 1/20 0.42
▸ RAB9A P51151 1/20 0.42
▸ GSK3B P49841 2/20 0.41
▸ SLC6A2 P23975 1/20 0.40
▸ SLC6A4 P31645 1/20 0.40
▸ FAAH O00519 1/20 0.40
▸ USP2 O75604 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31546427 0.90 TSHR (0.50) LMNATSHRHTTSMN1; SMN2TP53
SCHEMBL30584775 0.88 LMNA (0.49) LMNATSHRHTTSMN1; SMN2TP53
SCHEMBL31546418 0.82 LMNA (0.72) LMNATSHRHTTSMN1; SMN2TP53
SCHEMBL30584892 0.82 MEN1 (0.59) LMNATSHRHTTSMN1; SMN2TP53
SCHEMBL30584882 0.79 LMNA (0.46) LMNATSHRHTTSMN1; SMN2TP53
SCHEMBL25433518 0.79 MEN1 (0.56) LMNATSHRHTTSMN1; SMN2TP53
SCHEMBL31667543 0.79 LMNA (0.58) LMNATSHRHTTSMN1; SMN2TP53
SCHEMBL30584895 0.79 LMNA (0.45) LMNATSHRHTTSMN1; SMN2TP53
SCHEMBL30584804 0.78 MEN1 (0.60) LMNATSHRHTTSMN1; SMN2TP53
SCHEMBL30584805 0.78 LMNA (0.48) LMNATSHRHTTSMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 — — EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 LMNA 1344/4885TSHR 4347/4885HTT 2290/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 LMNA 1344/4885TSHR 4347/4885HTT 2290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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