Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP46A1 | Q9Y6A2 | 3/20 | 0.54 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKLR | P30613 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | DTYMK | P23919 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1088021 | 1.00 | CYP46A1 (0.54) | CYP46A1GPR119OPRD1OPRK1POLB | |
| SCHEMBL31735206 | 0.88 | GPR119 (0.47) | CYP46A1GPR119OPRD1OPRK1POLB | |
| SCHEMBL25400769 | 0.87 | GPR119 (0.50) | CYP46A1GPR119OPRD1OPRK1POLB | |
| SCHEMBL20137533 | 0.87 | GPR119 (0.50) | GPR119OPRD1OPRK1POLBGRM5 | |
| SCHEMBL29506047 | 0.87 | GPR119 (0.50) | GPR119OPRD1OPRK1POLBGRM5 | |
| SCHEMBL20137772 | 0.86 | GPR119 (0.49) | GPR119OPRD1OPRK1POLBGRM5 | |
| SCHEMBL25225903 | 0.86 | GPR119 (0.49) | CYP46A1GPR119OPRD1OPRK1POLB | |
| SCHEMBL18695971 | 0.85 | GPR119 (0.47) | GPR119OPRD1OPRK1POLBGRM5 | |
| SCHEMBL25276674 | 0.85 | GPR119 (0.48) | GPR119OPRD1OPRK1POLBGRM5 | |
| SCHEMBL2904379 | 0.85 | OPRD1 (0.48) | GPR119OPRD1OPRK1POLBGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113683610-B | RET inhibitor, pharmaceutical composition and application thereof | 广东东阳光药业股份有限公司 | 2025-02-25 | — | — | CN | disclosed |
| EP-4463452-A2 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | Anima Biotech Inc. (US) | 2024-11-20 | — | — | EP | disclosed |
| WO-2023177700-A2 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2023-09-21 | — | — | WO | disclosed |