SCHEMBL30585331

SCHEMBL30585331

CC(=O)n1ccn2ccnc12

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.32
ELANE P08246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9502453 0.74
SCHEMBL11425272 0.72
SCHEMBL1666896 0.71 NOTUM (0.34) NOTUMELANE
SCHEMBL26806860 0.71
SCHEMBL26806858 0.71
SCHEMBL28746087 0.68 ALPG (0.41) ELANE
SCHEMBL5490853 0.67
SCHEMBL26806855 0.67 ELANE (0.43) NOTUMELANE
SCHEMBL27690028 0.63 AGTR1 (0.41)
SCHEMBL1733874 0.63 NOTUM (0.41) NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4514802-A1 IMIDAZOLE DERIVATIVES AS ALK5 INHIBITORS Chiesi Farmaceutici S.p.A. (IT) 2025-03-05 EP disclosed
WO-2023208986-A1 IMIDAZOLE DERIVATIVES AS ALK5 INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2023-11-02 WO disclosed