Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.32 |
| ▸ | LPO | P22079 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11731712 | 0.88 | NOTUM (0.39) | NOTUMNOX1KMT2AKDM4EMEN1 | |
| SCHEMBL5148415 | 0.74 | NOTUM (0.41) | NOTUMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8677952 | 0.67 | NOTUM (0.48) | NOTUMNOX1KMT2AKDM4EMEN1 | |
| SCHEMBL6329634 | 0.67 | — | — | |
| SCHEMBL11052781 | 0.66 | POLB (0.33) | NOTUMPOLB | |
| SCHEMBL3302482 | 0.65 | POLB (0.40) | MAPK1KMT2AKDM4EMEN1ALDH1A1 | |
| Acetone SCHEMBL23855777 | 0.55 | — | — | |
| Acetone SCHEMBL3290016 | 0.55 | LMNA (0.86) | KDM4EALDH1A1 | |
| Acetone SCHEMBL4400462 | 0.55 | — | — | |
| Acetone SCHEMBL28986835 | 0.55 | LMNA (0.86) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004013207-A1 | POLYMETHYLENE AMINE, METHOD FOR THE PRODUCTION AND USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2004-02-12 | — | — | WO | claimed |
| US-5783169-A | RADIOIMMUNOCONJUGATED; DIAGNOSTIC AND THERAPY | BROOKHAVEN SCIENCE ASSOCIATES LLC (US) | 1998-07-21 | — | — | US | claimed |
| US-12108655-B2 | Organometallic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2024-10-01 | — | — | US | disclosed |
| US-20210399241-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-12-23 | — | — | US | disclosed |
| US-20210399241-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-12-23 | — | — | US | disclosed |
| CN-113725388-A | Organometallic compound and organic light emitting device including the same | 三星显示有限公司 | 2021-11-30 | — | — | CN | disclosed |
| US-20180265613-A1 | SEQUESTRANTS OF ADVANCED GLYCATION END PRODUCT (AGE) PRECURSORS | GENZYME CORPORATION | 2018-09-20 | — | — | US | disclosed |
| EP-1902077-B2 | NEUTRALISED CATIONIC POLYMER, COMPOSITION CONTAINING SAID POLYMER AND A COSMETIC TREATMENT METHOD | OREAL (FR) | 2018-07-18 | — | — | EP | disclosed |
| US-10004923-B2 | Neutralised cationic polymer, composition containing said polymer and a cosmetic treatment method | L'OREAL (FR) | 2018-06-26 | — | — | US | disclosed |
| US-10004923-B2 | Neutralised cationic polymer, composition containing said polymer and a cosmetic treatment method | L'OREAL (FR) | 2018-06-26 | — | — | US | disclosed |
| US-20160024233-A1 | SEQUESTRANTS OF ADVANCED GLYCATION END PRODUCT (AGE) PRECURSORS | GENZYME CORPORATION | 2016-01-28 | — | — | US | disclosed |
| EP-0065165-A1 | 5-Oxymethyl-4-acyl-1,3-dihydro-2H-imidazol-2-ones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1982-11-24 | — | — | EP | disclosed |
| EP-0064707-A1 | 4-(4-Phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1982-11-17 | — | — | EP | disclosed |
| EP-0064706-A1 | 5-(4-Phenyl-1-piperidinyl)methyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1982-11-17 | — | — | EP | disclosed |
| EP-0064704-A1 | 4-Aminomethyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1982-11-17 | — | — | EP | disclosed |
| EP-0064705-A1 | 5-Aminomethyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1982-11-17 | — | — | EP | disclosed |
| US-4329470-A | CORDIOTONIC, HYPOTENSIVE, ANTITHROMBOSIS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1982-05-11 | — | — | US | disclosed |
| US-4329471-A | CARDIOTONICS, HYPOTENSIVE AGENTS, AND ANTITHROMBOTIC AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1982-05-11 | — | — | US | disclosed |
| US-4294973-A | Process for the preparation of diacylated 4-imidazolin-2-ones | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-13 | — | — | US | disclosed |
| US-4238618-A | Process for the preparation of diacylated 4-imidazolin-2-ones | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210399241-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | LEF1, CRY1, ODC1 | NOTUM 1161/4885MAPK1 2126/4885NOX1 246/4885 |
| US-12108655-B2 | Organometallic compound and organic light-emitting device including the same | LEF1, CRY1, ODC1 | NOTUM 1161/4885MAPK1 2126/4885NOX1 246/4885 |
| US-10004923-B2 | Neutralised cationic polymer, composition containing said polymer and a cosmetic treatment method | KRT18, EYA3, EYA2 | NOTUM 92/4885MAPK1 1345/4885NOX1 4014/4885 |
| US-20180265613-A1 | SEQUESTRANTS OF ADVANCED GLYCATION END PRODUCT (AGE) PRECURSORS | AGER, FNTA, FABP2 | NOTUM 1300/4885MAPK1 3663/4885NOX1 2647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.