⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12703405 | 0.78 | MAOA (0.36) | — | |
| SCHEMBL3416543 | 0.76 | SLC7A5 (0.40) | — | |
| SCHEMBL3416544 | 0.76 | SLC7A5 (0.40) | — | |
| SCHEMBL10408938 | 0.76 | SLC7A5 (0.40) | — | |
| SCHEMBL21776623 | 0.74 | — | — | |
| SCHEMBL21785 | 0.73 | — | — | |
| SCHEMBL15795937 | 0.73 | — | — | |
| SCHEMBL1485441 | 0.73 | — | — | |
| SCHEMBL10869084 | 0.72 | CYP1A2 (0.39) | — | |
| SCHEMBL11508159 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2988597-B1 | MACROLIDES AND METHODS OF THEIR PREPARATION AND USE | HARVARD COLLEGE (US) | 2022-06-08 | — | — | EP | disclosed |
| US-11247994-B2 | 6-dithio-substituted-2′-deoxyguanosine compound, preparation method thereof and use thereof | ZHEJIANG UNIVERSITY (CN) | 2022-02-15 | — | — | US | disclosed |
| WO-2021242923-A1 | TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | AXIAL THERAPEUTICS, INC. (US) | 2021-12-02 | — | — | WO | disclosed |
| US-20210130356-A1 | 6-DITHIO-SUBSTITUTED-2'-DEOXYGUANOSINE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | ZHEJIANG UNIVERSITY (CN) | 2021-05-06 | — | — | US | disclosed |
| CN-109053841-B | 6-disulfur substituted-2' -deoxyguanosine compound and preparation method and application thereof | 浙江大学 | 2020-11-17 | — | — | CN | disclosed |
| US-10379105-B2 | Antibodies to aripiprazole haptens and use thereof | JANSSEN PHARMACEUTICA NV (BE) | 2019-08-13 | — | — | US | disclosed |
| US-10246478-B2 | Polyene macrolide derivative | SHIONOGI & CO., LTD. (JP) | 2019-04-02 | — | — | US | disclosed |
| CN-109053841-A | The bis- sulphur of 6- replace -2 '-deoxyguanosine class compounds and its preparation method and application | 浙江大学 | 2018-12-21 | — | — | CN | disclosed |
| US-20170204198-A1 | Antibodies to Aripiprazole Haptens and Use Thereof | JANSSEN PHARMACEUTICA NV (BE) | 2017-07-20 | — | — | US | disclosed |
| US-20170190729-A1 | POLYENE MACROLIDE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2017-07-06 | — | — | US | disclosed |
| US-20040016910-A1 | Non-toxic corrosion-protection rinses and seals based on rare earth elements | DAYTON, UNIVERSITY OF | 2004-01-29 | — | — | US | disclosed |
| US-20040011252-A1 | Non-toxic corrosion-protection pigments based on manganese | UNIVERSITY OF DAYTON | 2004-01-22 | — | — | US | disclosed |
| US-20030234063-A1 | Non-toxic corrosion-protection conversion coats based on cobalt | DAYTON, UNIVERSITY OF | 2003-12-25 | — | — | US | disclosed |
| US-20030230363-A1 | Non-toxic corrosion-protection rinses and seals based on cobalt | UNIVERSITY OF DAYTON | 2003-12-18 | — | — | US | disclosed |
| WO-2003060192-A1 | NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003060191-A2 | NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003060019-A1 | NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| US-5904857-A | REMOVAL OF DISSOLVED OXYGEN FROM ALKALINE WATER | NALCO CHEMICAL COMPANY (US) | 1999-05-18 | — | — | US | disclosed |
| CN-1200357-A | 4-alkyl semicarbazides as oxygen scavengers | NALCO CHEMICAL CO (US) | 1998-12-02 | — | — | CN | disclosed |
| EP-0875604-A1 | Substituted semicarbazides as oxygen scavengers | NALCO CHEMICAL COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |